Songqing Fan Selected Research

Therapeutics

8/2023	New insights into the important roles of phase seperation in the targeted therapy of lung cancer.
1/2023	RNF126-Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple-Negative Breast Cancer to Radiotherapy.
1/2023	Mutual connected IL-6, EGFR and LIN28/Let7-related mechanisms modulate PD-L1 and IGF upregulation in HNSCC using immunotherapy.
2/2022	Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma.
1/2022	Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer.
1/2022	The multiple roles and therapeutic potential of HSP60 in cancer.
12/2021	Genomic profiles and their associations with TMB, PD-L1 expression, and immune cell infiltration landscapes in synchronous multiple primary lung cancers.
10/2021	Membrane-Associated RING-CH 8 Functions as a Novel PD-L1 E3 Ligase to Mediate PD-L1 Degradation Induced by EGFR Inhibitors.
1/2021	Downregulation of death receptor 4 is tightly associated with positive response of EGFR mutant lung cancer to EGFR-targeted therapy and improved prognosis.
1/2021	Long non-coding RNA AFAP1-AS1 accelerates lung cancer cells migration and invasion by interacting with SNIP1 to upregulate c-Myc.

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Songqing Fan Research Topics

Disease

90	Neoplasms (Cancer) 05/2024 - 08/2009
37	Nasopharyngeal Carcinoma 01/2024 - 02/2005
32	Neoplasm Metastasis (Metastasis) 11/2023 - 03/2007
21	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2024 - 03/2012
21	Carcinogenesis 01/2024 - 07/2005
16	Lymphatic Metastasis 08/2020 - 09/2012
13	Lung Neoplasms (Lung Cancer) 08/2023 - 03/2012
11	Breast Neoplasms (Breast Cancer) 01/2022 - 07/2011
8	Squamous Cell Carcinoma of Head and Neck 11/2023 - 04/2010
7	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/2024 - 01/2021
7	Adenocarcinoma of Lung 01/2023 - 01/2019
5	Carcinoma (Carcinomatosis) 05/2024 - 09/2012
5	Inflammation (Inflammations) 01/2023 - 01/2014
4	Colorectal Neoplasms (Colorectal Cancer) 02/2020 - 06/2009
4	Nasopharyngeal Neoplasms (Cancer of the Nasopharynx) 11/2019 - 09/2012
2	Pathologic Processes 01/2020 - 03/2019
2	Disease Progression 10/2019 - 06/2019
2	Lung Diseases (Lung Disease) 08/2019 - 01/2019
2	Ductal Carcinoma 01/2018 - 10/2014
2	Hyperplasia 01/2018 - 01/2014
2	Colitis 10/2017 - 01/2014
2	Astrocytoma (Pilocytic Astrocytoma) 01/2017 - 01/2017
2	Infections 01/2017 - 01/2012
2	Glioma (Gliomas) 01/2017 - 07/2011
2	Pancreatic Neoplasms (Pancreatic Cancer) 03/2016 - 04/2010
2	Epstein-Barr Virus Infections 12/2015 - 01/2012
1	Esophageal Squamous Cell Carcinoma 05/2024
1	Myositis (Idiopathic Inflammatory Myopathies) 12/2023
1	Dermatomyositis (Dermatopolymyositis) 12/2023

Drug/Important Bio-Agent (IBA)

44	Proteins (Proteins, Gene)FDA Link 01/2024 - 07/2005
16	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2013
13	Messenger RNA (mRNA)IBA 01/2024 - 06/2012
11	Eukaryotic Initiation Factor-4EIBA 01/2023 - 08/2009
9	Peptide Initiation Factors (Initiation Factor)IBA 01/2022 - 08/2009
9	Cyclin D1IBA 08/2020 - 05/2009
8	Phosphotransferases (Kinase)IBA 09/2023 - 01/2013
7	osimertinibIBA 03/2024 - 01/2020
7	MicroRNAs (MicroRNA)IBA 01/2020 - 07/2011
5	ErbB Receptors (EGF Receptor)IBA 09/2023 - 01/2019
5	CateninsIBA 07/2023 - 07/2013
5	B7-H1 AntigenIBA 02/2022 - 10/2020
4	RNA (Ribonucleic Acid)IBA 01/2021 - 03/2007
4	Complementary DNA (cDNA)IBA 11/2014 - 02/2007
3	Carrier Proteins (Binding Protein)IBA 01/2024 - 04/2010
3	tyrosine receptor (receptor, tyrosine)IBA 09/2023 - 08/2020
3	LigandsIBA 01/2023 - 01/2019
3	Insulin Receptor Substrate ProteinsIBA 01/2023 - 01/2014
3	Small Interfering RNA (siRNA)IBA 01/2023 - 04/2010
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2023 - 07/2011
3	Long Noncoding RNAIBA 01/2022 - 02/2020
3	Everolimus FDA Link 01/2022 - 05/2016
3	TOR Serine-Threonine KinasesIBA 01/2021 - 05/2016
3	ParaffinIBA 01/2021 - 01/2017
3	Untranslated RNA (Noncoding RNA)IBA 02/2020 - 10/2013
3	CGP 57380IBA 10/2019 - 05/2016
3	Paclitaxel (Taxol)FDA LinkGeneric 03/2019 - 01/2015
3	Chaperonin 10IBA 01/2017 - 01/2017
3	LactoferrinIBA 02/2015 - 01/2012
3	flotillinsIBA 01/2015 - 01/2014
2	Etoposide (VP 16)FDA LinkGeneric 03/2024 - 04/2012
2	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2024 - 01/2022
2	UbiquitinIBA 12/2023 - 01/2022
2	EnzymesIBA 12/2023 - 03/2019
2	somatostatin receptor 2IBA 11/2023 - 09/2023
2	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 01/2021
2	SurvivinIBA 01/2023 - 04/2010
2	Transcription Factors (Transcription Factor)IBA 01/2023 - 01/2021
2	Matrix Metalloproteinases (MMPs)IBA 01/2021 - 01/2017
2	TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA 01/2021 - 08/2010
2	Programmed Cell Death 1 ReceptorIBA 01/2021 - 01/2020
2	Indicators and Reagents (Reagents)IBA 08/2020 - 01/2020
2	Histone Deacetylase InhibitorsIBA 01/2020 - 04/2010
2	PanobinostatIBA 01/2020 - 04/2010
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 11/2019 - 11/2014
2	LipidsIBA 09/2018 - 01/2015
2	Estrogens (Estrogen)FDA Link 01/2017 - 03/2012
2	VimentinIBA 01/2017 - 06/2014
2	Progesterone Receptors (Progesterone Receptor)IBA 01/2017 - 03/2012
2	Eukaryotic Initiation Factor-4G (Eukaryotic Initiation Factor 4G)IBA 04/2016 - 04/2010
2	Phenobarbital (Luminal)FDA Link 01/2015 - 03/2012
2	Epidermal Growth Factor (EGF)IBA 01/2015 - 02/2005
2	Epstein-Barr virus encoded RNA 1IBA 10/2013 - 05/2009
2	Caspase 8 (Caspase-8)IBA 04/2013 - 08/2010
1	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2024
1	trioctyl phosphine oxide (TOPO)IBA 03/2024
1	Type II DNA Topoisomerases (Topoisomerase II)IBA 03/2024
1	PolyaminesIBA 01/2024
1	CollagenIBA 01/2024
1	ras ProteinsIBA 01/2024
1	AutoantibodiesIBA 12/2023
1	Nuclear Matrix-Associated ProteinsIBA 12/2023
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 11/2023
1	Circular RNAIBA 11/2023
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 09/2023
1	NF-kappa B (NF-kB)IBA 09/2023
1	Immune Checkpoint InhibitorsIBA 07/2023

Therapy/Procedure

22	Therapeutics 08/2023 - 04/2007
11	Drug Therapy (Chemotherapy) 07/2023 - 01/2014
10	Radiotherapy 05/2024 - 01/2014
6	Immunotherapy 01/2023 - 12/2019